Epithalon

What it is

Epithalon (also written Epitalon) is a four-amino-acid synthetic peptide developed from an extract of the pineal gland. It is studied mainly in cellular senescence, telomerase and circadian models.

Where it has been studied

• Telomerase activity in cultured cells
• Pineal and melatonin regulation models
• Lifespan studies in rodents

Selected literature

• Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising PropertiesAraj SK et al. · Int J Mol Sci, 2025 · PMID 40141333
• The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic RetinopathyGatta M et al. · Stem Cell Rev Rep, 2025 · PMID 40493162
• Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitroYue X et al. · Aging (Albany NY), 2022 · PMID 35413689

PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.