Thymosin alpha-1

What it is

Thymosin alpha-1 is a naturally occurring acetylated peptide originally isolated from thymic tissue. It has been used clinically as thymalfasin in some countries and is a reference compound in innate and adaptive immunity research.

Where it has been studied

• Dendritic cell and T-cell activation
• Toll-like receptor signalling
• Infection and vaccine-adjuvant models

Selected literature

• Thymosin alpha-1Ancell CD et al. · Am J Health Syst Pharm, 2001 · PMID 11381492
• Aging and Thymosin Alpha-1Simonova MA et al. · Int J Mol Sci, 2025 · PMID 41373628
• Thymosin alpha-1 treatment in chronic hepatitis BWu X et al. · Expert Opin Biol Ther, 2015 · PMID 25640173

PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.