GHK-Cu
What it is
GHK-Cu is a naturally occurring tripeptide with a high affinity for copper(II) ions. Found in human plasma, saliva and urine, its concentration declines with age. It is one of the best-documented peptides in skin and wound biology.
Where it has been studied
- Collagen and glycosaminoglycan synthesis in fibroblast cultures
- Wound-healing and remodelling models
- Gene-expression profiling studies
Selected literature
- GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin RegenerationPickart L et al. · Biomed Res Int, 2015 · PMID 26236730
- The potential of GHK as an anti-aging peptideDou Y et al. · Aging Pathobiol Ther, 2020 · PMID 35083444
- GHK-Cu as a Bioactive Metallopeptide and Drug-Delivery Cargo: Coordination Chemistry, Formulation Science, Therapeutic Evidence, and a Translational RoadmapMateescu DM et al. · Pharmaceutics, 2026 · PMID 42797253
PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.
