Hexarelin

What it is

Hexarelin is a synthetic growth-hormone-releasing hexapeptide related to GHRP-6, with a methylated tryptophan residue. Alongside secretagogue studies it has been investigated for growth-hormone-independent effects on cardiac tissue.

Where it has been studied

• Growth hormone secretagogue receptor studies
• Cardioprotection models
• CD36 receptor binding studies

Selected literature

• The cardiovascular action of hexarelinMao Y et al. · J Geriatr Cardiol, 2014 · PMID 25278975
• Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathwayGuan C et al. · Eur J Med Res, 2023 · PMID 37710348
• Hexarelin attenuates abdominal aortic aneurysm formation by inhibiting SMC phenotype switch and inflammasome activationJiang B et al. · Microvasc Res, 2022 · PMID 34856183

PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.