KPV
What it is
KPV (Lys-Pro-Val) is the three-amino-acid C-terminal fragment of alpha-melanocyte-stimulating hormone. It retains the anti-inflammatory activity of the parent hormone without its pigmentation effects in research models.
Where it has been studied
- Colitis and intestinal inflammation models
- NF-kappa-B signalling in cell culture
- Skin inflammation studies
Selected literature
- Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel diseaseKannengiesser K et al. · Inflamm Bowel Dis, 2008 · PMID 18092346
- Effects of the COOH-terminal tripeptide alpha-MSH(11-13) on corneal epithelial wound healing: role of nitric oxideBonfiglio V et al. · Exp Eye Res, 2006 · PMID 16965771
- Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophoreBrzoska T et al. · Adv Exp Med Biol, 2010 · PMID 21222263
PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.
