Melanotan II
What it is
Melanotan II is a cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone that activates several melanocortin receptors. It is a tool compound in melanogenesis and melanocortin signalling research.
Where it has been studied
- Melanocortin receptor pharmacology
- Melanogenesis in melanocyte cultures
- Energy balance and behaviour models in rodents
Selected literature
- Melanotan II, a melanocortin agonist, partially rescues the impaired thermogenic capacity of pituitary adenylate cyclase-activating polypeptide deficient miceMcMillan TR et al. · Exp Physiol, 2021 · PMID 33332767
- Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for foodEliason NL et al. · Neuropeptides, 2022 · PMID 36155088
- Melanotan-II reverses memory impairment induced by a short-term HF dietWekwejt P et al. · Biomed Pharmacother, 2023 · PMID 37478579
PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.
