VIP
What it is
VIP is a neuropeptide of the secretin and glucagon family, found in the gut, pancreas and nervous system. It acts on the VPAC1 and VPAC2 receptors and is a standard reagent in neuroimmunology and smooth-muscle research.
Where it has been studied
- VPAC receptor pharmacology
- Smooth-muscle relaxation assays
- Neuroimmune and circadian studies
Selected literature
- Elucidation of vasoactive intestinal peptide pharmacophore for VPAC(1) receptors in human, rat, and guinea pigIgarashi H et al. · J Pharmacol Exp Ther, 2002 · PMID 11907155
- Elucidation of the vasoactive intestinal peptide pharmacophore for VPAC(2) receptors in human and rat and comparison to the pharmacophore for VPAC(1) receptorsIgarashi H et al. · J Pharmacol Exp Ther, 2002 · PMID 12388623
- Development of simplified vasoactive intestinal peptide analogs with receptor selectivity and stability for human vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptorsIgarashi H et al. · J Pharmacol Exp Ther, 2005 · PMID 15994369
PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.
