5-Amino-1MQ
Small-molecule NNMT inhibitor for adipose and metabolic research
5 mg vial · 50 mg vial
from € 35.00
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small molecule · also known as Acadesine
AICAR
An AMPK activator widely used in energy-metabolism research.
AICAR · 50 mg · Lyophilised vial
small molecule · also known as Acadesine
AICAR
An AMPK activator widely used in energy-metabolism research.
€ 35.00per vial, EUR
In stock
Presentation1 option
What it is
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide, acadesine) is a small-molecule analogue of AMP. Inside cells it is phosphorylated to ZMP, which activates AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance.
Where it has been studied
- AMPK signalling in cell culture
- Glucose uptake and mitochondrial biogenesis models
- Exercise-mimetic studies in rodents
Selected literature
- Administration of AICAR, an AMPK Activator, Prevents and Reverses Diabetic Polyneuropathy (DPN) by Regulating MitophagyChandrasekaran K et al. · Int J Mol Sci, 2024 · PMID 39795939
- AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathwayTsogbadrakh B et al. · Biochem Biophys Res Commun, 2019 · PMID 30616891
- Prior treatment with the AMPK activator AICAR induces subsequently enhanced glucose uptake in isolated skeletal muscles from 24-month-old ratsOki K et al. · Appl Physiol Nutr Metab, 2018 · PMID 29518344
PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.
Specifications
| Compound | AICAR (Acadesine) |
|---|---|
| Type | Small molecule |
| Selected presentation | 50 mg · Lyophilised vial |
| Form | Lyophilised powder in a sealed glass vial |
| Fill volume and concentration | Not applicable (lyophilised) |
| Label | CELVIVE wordmark, compound name, amount, "Purity: >99%", "For research use only" |
| Storage | -20 °C for long-term storage; 2 to 8 °C for under three months; away from light |
| Certificate of analysis | Not yet published online. Request for a batch |
| Research areas | Metabolic & GLP research |
| All presentations | 50 mg lyophilised vial · € 35.00 |
Handling
- Lyophilised peptides tolerate room temperature for several weeks in transit. Move to cold storage on receipt.
- Reconstituted vials are typically used within three to four weeks at 2 to 8 °C; stability varies by compound.
- Opened or unsealed vials cannot be returned. Transit damage must be documented within 24 hours.
Same research area
