small molecule · also known as NNMT inhibitor

5-Amino-1MQ

A small-molecule NNMT inhibitor used in adipose and metabolic research.

5-Amino-1MQ · 5 mg · Lyophilised vial

small molecule · also known as NNMT inhibitor

5-Amino-1MQ

A small-molecule NNMT inhibitor used in adipose and metabolic research.

€ 35.00per vial, EUR

In stock

Presentation2 options

5 mg · Lyophilised vial€ 35.00 50 mg · Lyophilised vial€ 70.00

Lyophilised powder in a sealed glass vial

Storage: -20 °C for long-term storage; 2 to 8 °C for under three months; away from light

Tracked shipping EUR 9.95 per order. Benelux 1 to 2 business days, Germany and France 2 to 3, rest of Europe 3 to 5. Details

Batch certificate: not yet published online. Request one for this presentation.

Research use only. Not for human or veterinary use.

What it is

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a membrane-permeable small molecule, not a peptide, that inhibits nicotinamide N-methyltransferase (NNMT), an enzyme expressed in adipose tissue and liver. It is supplied as a research reagent.

Where it has been studied

NNMT inhibition and nicotinamide / NAD+ metabolism in cell and rodent models
Adipocyte biology and diet-induced obesity models
Muscle progenitor cell studies

Selected literature

Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO miceDimet-Wiley A et al. · Sci Rep, 2022 · PMID 35013352
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cellsAkar S et al. · J Obstet Gynaecol, 2021 · PMID 33645410

PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.

Specifications

Compound	5-Amino-1MQ (NNMT inhibitor)
Type	Small molecule
Selected presentation	5 mg · Lyophilised vial
Form	Lyophilised powder in a sealed glass vial
Fill volume and concentration	Not applicable (lyophilised)
Label	CELVIVE wordmark, compound name, amount, "Purity: >99%", "For research use only"
Storage	-20 °C for long-term storage; 2 to 8 °C for under three months; away from light
Certificate of analysis	Not yet published online. Request for a batch
Research areas	Metabolic & GLP research, Longevity & mitochondrial
All presentations	5 mg lyophilised vial · € 35.00 50 mg lyophilised vial · € 70.00

Handling

Lyophilised peptides tolerate room temperature for several weeks in transit. Move to cold storage on receipt.
Reconstituted vials are typically used within three to four weeks at 2 to 8 °C; stability varies by compound.
Opened or unsealed vials cannot be returned. Transit damage must be documented within 24 hours.

Storage and stability FAQ