small molecule · also known as Acadesine

AICAR

An AMPK activator widely used in energy-metabolism research.

AICAR · 50 mg · Lyophilised vial

small molecule · also known as Acadesine

AICAR

An AMPK activator widely used in energy-metabolism research.

€ 35.00per vial, EUR

In stock

Presentation1 option

50 mg · Lyophilised vial€ 35.00

Lyophilised powder in a sealed glass vial

Storage: -20 °C for long-term storage; 2 to 8 °C for under three months; away from light

Tracked shipping EUR 9.95 per order. Benelux 1 to 2 business days, Germany and France 2 to 3, rest of Europe 3 to 5. Details

Batch certificate: not yet published online. Request one for this presentation.

Research use only. Not for human or veterinary use.

What it is

AICAR (5-aminoimidazole-4-carboxamide ribonucleotide, acadesine) is a small-molecule analogue of AMP. Inside cells it is phosphorylated to ZMP, which activates AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance.

Where it has been studied

AMPK signalling in cell culture
Glucose uptake and mitochondrial biogenesis models
Exercise-mimetic studies in rodents

Selected literature

Administration of AICAR, an AMPK Activator, Prevents and Reverses Diabetic Polyneuropathy (DPN) by Regulating MitophagyChandrasekaran K et al. · Int J Mol Sci, 2024 · PMID 39795939
AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathwayTsogbadrakh B et al. · Biochem Biophys Res Commun, 2019 · PMID 30616891
Prior treatment with the AMPK activator AICAR induces subsequently enhanced glucose uptake in isolated skeletal muscles from 24-month-old ratsOki K et al. · Appl Physiol Nutr Metab, 2018 · PMID 29518344

PubMed records selected for relevance to the compound. They describe published research, not outcomes or uses.

Specifications

Compound	AICAR (Acadesine)
Type	Small molecule
Selected presentation	50 mg · Lyophilised vial
Form	Lyophilised powder in a sealed glass vial
Fill volume and concentration	Not applicable (lyophilised)
Label	CELVIVE wordmark, compound name, amount, "Purity: >99%", "For research use only"
Storage	-20 °C for long-term storage; 2 to 8 °C for under three months; away from light
Certificate of analysis	Not yet published online. Request for a batch
Research areas	Metabolic & GLP research
All presentations	50 mg lyophilised vial · € 35.00

Handling

Lyophilised peptides tolerate room temperature for several weeks in transit. Move to cold storage on receipt.
Reconstituted vials are typically used within three to four weeks at 2 to 8 °C; stability varies by compound.
Opened or unsealed vials cannot be returned. Transit damage must be documented within 24 hours.

Storage and stability FAQ